Identifying and localizing intracellular nanoparticles using Raman spectroscopy

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Identifying and localizing intracellular nanoparticles using Raman spectroscopy.

Raman microscopy is employed to spectroscopically image biological cells previously exposed to fluorescently labelled polystyrene nanoparticles and, in combination with K-means clustering and principal component analysis (PCA), is demonstrated to be capable of localising the nanoparticles and identifying the subcellular environment based on the molecular spectroscopic signatures. The neutral na...

متن کامل

Nanoparticles and intracellular applications of surface-enhanced Raman spectroscopy

Surface-enhanced Raman spectrocopy (SERS) offers ultrasensitive vibrational fingerprinting at the nanoscale. Its non-destructive nature affords an ideal tool for interrogation of the intracellular environment, detecting the localisation of biomolecules, delivery and monitoring of therapeutics and for characterisation of complex cellular processes at the molecular level. Innovations in nanotechn...

متن کامل

Biosensing Based on Surface-Enhanced Raman Spectroscopy by Using Metal Nanoparticles

Surface-enhanced Raman spectroscopy (SERS) is a promising tool in the analytical science because it provides good selectivity and sensitivity without the labeling process required by fluorescence detection. This technique consists of locating the target analyte on nanometer range of roughed Au-nanoparticles. The presence of the metal nanoparticles provides a tremendous enhancement to the result...

متن کامل

Unification of Surface Enhanced Raman Spectroscopy of Dyes Using One Pot Synthesized Stabilized Ag Nanoparticles

stabilized Ag Nanoparticles (NPs) were synthesized using Lee-Meisel method under three different conditions in an oil bath. UV-Vis spectroscopy of the Ag NPs showed a Localized Surface Plasmon (LSP) band around 430 nm, indicating Ag NPs had a size range around 40 nm. To fabricate a surface Enhanced Raman Spectroscopy (SERS) substrate, LSP properties of Ag NPs was employed with the goal of detec...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Analyst

سال: 2012

ISSN: 0003-2654,1364-5528

DOI: 10.1039/c2an15977e